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. Author manuscript; available in PMC: 2019 Mar 19.
Published in final edited form as: Nature. 2018 Sep 19;562(7728):578–582. doi: 10.1038/s41586-018-0543-y

Extended Data Figure 1. Senescent cells accumulate in PS19 mice.

Extended Data Figure 1.

RT-qPCR analysis for senescence-associated genes in hippocampi (left) and cortices (right) of 3- and 10-month-old male mice (animal numbers indicated in the legend, 2 independent experiments; normalized to 3 m Wildtype group). Data are mean ± s.e.m. *P < 0.05; **P < 0.01; ***P < 0.001 (one-way ANOVA with Tukey’s multiple comparisons test). Exact P values can be found in the accompanying source data file.