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. 2018 Oct 16;2018:4308054. doi: 10.1155/2018/4308054

Table 3.

Effect of exposure to some natural insecticides on body and organs weight in experimental animals.

Insecticide Treatment Dose 
mg/kg. b.wt. or animal/day
Duration 
(days)
Test animal Organ Reference
Pyrethrum oral 200 23 rat (♂) body, liver, [52]
Abamectin oral 3.802 14 mice (♂) body, liver, kidney [57]
Abamectin oral 22.10 21 rat (♀, ♂) body, liver, kidney [60]
Spinosad oral 350 28 mice (♂) body, kidney, spleen, [68]
Spinosad oral 10, 50, 200 21 rat (♀, ♂) body [69]
2.5, 10, 50 28 rabbits (♀) body
Bt fed 300, 30 30 rat (♂) body, liver, kidney [78]
Phosphine inhalation 3 g of phostoxin tablet (1.5 hrs/day) 7 rat (♂) body, kidney [72]
Phosphine inhalation 0.5, 1.5 and 4.5 mg/m3 (6hrs/day) 13 (weeks) rat (♀, ♂) body [55]
Azadirachtin oral 500, 1000, 1500 90 rat (♀, ♂) body, liver, kidney, testis, spleen, heart, lung [75]
Bt oral, dermal 3,4,5 ml 1 rat (♀,♂), rabbit (♀,♂) body, liver, kidney [77]
Azadirachtin fed 5, 25, 50 70 rat (♀, ♂) body, liver, kidney, brain [76]

Male (♂), female (♀), increase “”, decrease “”, and no change “without symbol”. Bt: Bacillus thuringiensis.