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. 2018 Oct 30;15:300. doi: 10.1186/s12974-018-1334-y

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — The frequency of CD19⁺CD24^hiCD38^hi cells is decreased during relapse post alemtuzumab treatment. a Flow-cytometry plot of expression of CD24 and CD38 in total CD19⁺ B cells. b Graph showing the clinical course. The frequency and the absolute number of CD19⁺CD24^hiCD38^hi B cells and infusion of 2 cycles of alemtuzumab are shown. Filled circles indicate the frequency of CD19⁺CD24^hiCD38^hi B cells, and hollow circles indicate the absolute number of CD19⁺CD24^hiCD38^hi B cells. Red arrow indicates relapse