Table 1.
Characteristics of idiopathic infertile males and fertile controls
| Characteristic | Controls (n = 59)a | Cases | |||
|---|---|---|---|---|---|
| Case 1 (n = 39)b | Case 2 (n = 45)c | Case 3 (n = 51)d | Case all (n = 135)e | ||
| Age (years, mean ± SD) | 29.08 ± 3.85 | 29.85 ± 4.84 | 28.71 ± 3.91 | 28.78 ± 4.07 | 29.07 ± 4.25 |
| BMI (kg/m2, mean ± SD)f | 23.93 ± 4.17 | 22.61 ± 3.54 | 22.99 ± 2.72 | 22.92 ± 3.36 | 22.86 ± 3.20 |
| Smoking status [n (%)] | |||||
| No | 27 (45.8) | 21 (53.8) | 26 (57.8) | 23 (45.1) | 70 (51.9) |
| Yes | 32 (54.2) | 18 (46.2) | 19 (42.2) | 28 (54.9) | 65 (48.1) |
| Alcohol drinking [n (%)] | |||||
| No | 46 (78.0) | 33 (84.6) | 37 (82.2) | 41 (80.4) | 111 (82.2) |
| Yes | 13 (22.0) | 6 (15.4) | 8 (17.8) | 10 (19.6) | 24 (17.8) |
| Abstinence time [n (%)] | |||||
| < 4 | 15 (25.4) | 7 (18.3) | 10 (23.8) | 4 (12.1) | 21 (15.6) |
| 4–7 | 38 (64.4) | 41 (68.3) | 24 (57.1) | 23 (69.7) | 88 (65.2) |
| ≥ 7 | 6 (10.2) | 12 (13.3)g | 8 (19.0) | 6 (18.2) | 26 (19.3) |
| Ejaculate volume (ml, mean ± SD) | 4.29 ± 1.32 | 2.99 ± 1.21g | 3.30 ± 1.60g | 3.43 ± 1.47g | 3.26 ± 1.45g |
| Sperm concentration (106/ml, mean ± SD) | 49.52 ± 33.85 | 76.92 ± 54.36g | 14.62 ± 2.91g | 4.35 ± 2.75g | 28.74 ± 42.58g |
| Sperm motility (%, mean ± SD) | 57.00 ± 16.05 | 53.81 ± 26.54 | 39.59 ± 20.12g | 31.48 ± 14.70g | 40.64 ± 22.27g |
aControl: fertile men
bCase 1: idiopathic infertile men with normozoospermia (sperm concentration ≥ 20 × 106/ml)
cCase 2: idiopathic infertile men with moderate oligozoospermia (sperm concentration 5–20 × 106/ml)
dCase 3: idiopathic infertile men with severe oligozoospermia (sperm concentration < 5 × 106/ml)
eCase all: the sum of case 1, case 2, and case 3
fBMI body mass index
gP < 0.05 when compared between case and control groups