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. 2018 Oct 29;18:178. doi: 10.1186/s12883-018-1183-4

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Predominance of large granular lymphocytes in peripheral blood at the onset of Alemtuzumab-induced neutropenia. At the onset of neutropenia, peripheral blood smear analysis (Wright-Giemsa staining) revealed numerous large granular lymphocytes (LGL) (about 80–90%) that had azurophil granules in their cytoplasm (left image) and signs of cystic degeneration (right image, red arrow)