Table 1.
Group I (control) | Group II (busulfan) | Group III (recovery) | Group IV (G-CSF) | |
---|---|---|---|---|
Mean height of spermatogenic epithelium | 73.8±3.4 | 22.4±2.7* | 29.9±2.1* | 61.4±2.7** |
Mean number of of positive CD34 cells on day 5 | 0.00±0.00 | 2.3±1.3* | - | 15.7±2.1# |
Mean number of of positive CD34 cells after 4 weeks | 0.000.00 | 2.00±0.8* | - | 0.00±0.00† |
Mean number of positive CD34 cells after 6 weeks | - | - | 1.4±0.3∞ | - |
Mean number of positive PCNA cells | 48.9±2.6 | 7.2±1.3∞ | 16.5±2.1* | 39.2±2.6‡ |
Mean number of positive caspase-3 cells | 4.4±12 | 27.00±1.8∞ | 21.6±2.2* | 7.1±1.9** |
*Significant compared to Group I, **Significant compared to both Groups II and III but nonsignificant compared to Group I, #Significant compared to both Groups I, II, †Significant compared to Group II and IV on day 5, ∞Significant compared to Group I and Group IV, ‡Significant compared to Group II. PCNA: Proliferating cell nuclear antigen, G-CSF: Granulocyte colony-stimulating factors