Table 2.

Correlation between the expression of MTHFD1 and the clinicopathological features of lung carcinoma patients.

Features	Number of patients	Low MTHFD1 expression	High MTHFD1 expression	P value
Gender				0.784
Male	26	10 (76.9%)	16 (72.7%)
Female	9	3 (23.1%)	6 (27.3%)
Age(years)				0.229
<60	16	6 (35.3%)	10 (66.7%)
≥60	19	11 (64.7%)	5 (33.3%)
Tumor size (cm)				0.002*
<5	15	10 (76.9%)	5 (22.7%)
≥5	20	3 (23.1%)	17 (77.3%)
TNM stage				0.011*
I/II	10	7 (53.8%)	3 (13.6%)
III/IV	25	6 (46.2%)	19 (86.4%)
Histologic grade				0.048*
Well	3	2 (13.3%)	1 (5%)
Moderate	12	8 (53.3%)	4 (20%)
Poor	20	5 (33.3%)	15 (75%)
Metastasis				0.024*
No	23	15 (83.3%)	8 (47.1%)
Yes	12	3 (16.7%)	9 (52.9%)

^*P<0.05, Chi-square test.