Table 1.
Partial correlation of fractional anisotropy with PTSD severity: cingulum and uncinate tracts
| Tract/FA | CAPS score (full group) |
CAPS score (PTSD only) |
CAPS score (combat controls) |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| r | p | df | r | p | df | r | p | df | ||
| CAB (LH) | 0.433 | 0.001* | 57 | 0.534 | 0.005* | 24 | 0.141 | 0.492 | 24 | |
| CAB (RH) | –0.050 | 0.709 | 57 | 0.031 | 0.882 | 24 | –0.067 | 0.744 | 24 | |
| CCG (LH) | –0.037 | 0.780 | 57 | –0.190 | 0.352 | 24 | –0.324 | 0.106 | 24 | |
| CCG (RH) | –0.061 | 0.648 | 57 | –0.073 | 0.725 | 24 | –0.194 | 0.343 | 24 | |
| UNC (LH) | 0.002 | 0.986 | 57 | –0.072 | 0.727 | 24 | –0.048 | 0.817 | 24 | |
| UNC (RH) | –0.036 | 0.787 | 57 | –0.287 | 0.155 | 24 | –0.025 | 0.905 | 24 | |
*
Indicates significance if p ≤ 0.008.
Bonferroni method was used to adjust alpha threshold for multiple comparison (0.05/6 = 0.008).
FA, fractional anisotropy; LH, left hemisphere; RH, right hemisphere; CAPS, Clinician Administered PTSD Scale for DSM-IV; r, partial correlation controlling for age; sex, head motion, and antidepressant use; CAB, cingulum angular bundle; CCG, cingulum cingulate gyrus endings; UNC, uncinate fasciculus.