Table 3.
Comparison of SIBO‐positive versus SIBO‐negative group
| Parameters | SIBO positive (n = 13) | SIBO negative (n = 134) | P‐value |
|---|---|---|---|
| Total, n (%) | 13 (8.8) | 134 (91.2) | 0.018 |
| Age, n (range) (years) | 36 (25–43.5) | 40.5 (33–50.25) | 0.046 |
| Diarrhea, n (%) | 4 (30.8) | 29 (21.6) | 0.489 |
| Abdominal discomfort, n (%) | 12 (92.3) | 109 (81.3) | 0.466 |
| Flatulence, n (%) | 11 (84.6) | 77 (57.5) | 0.057 |
| Abdominal bloating, n (%) | 12 (92.3) | 106 (79.1) | 0.465 |
| Abdominal distension, n (%) | 8 (61.5) | 56 (41.8) | 0.170 |
| Gender, n (%) | |||
| Male | 8 (61.5) | 66 (49.3) | 0.398 |
| Female | 5 (38.5) | 68 (50.7) | |
| BMI (kg/m2) | 25.33 ± 5.49 | 25.35 ± 4.65 | 0.987 |
| Type of PPI, n (%) | |||
| Rabeprazole | 8 (61.5) | 84 (62.7) | 1.000 |
| Omeprazole | 0 (0.0) | 28 (20.9) | 0.130 |
| Pantoprazole | 5 (38.5) | 22 (16.4) | 0.064 |
| Duration of PPI (range) (months) | 8 (6–24) | 6 (4–18) | 0.071 |
| OCTT, n (range) (min) | 160 (140–172.50) | 120 (103.75–150.00) | 0.002 |
| OCTT, n (%) | |||
| Normal OCTT | 0 (0.0) | 37 (27.6) | 0.039 |
| Delayed OCTT | 13 (100) | 89 (70.6) | 0.023 |
| Fast OCTT | 0 (0.0) | 8 (6) | 1.000 |
BMI, body mass index; OCTT, orocecal transit time; PPI, proton pump inhibitor; SIBO, small intestinal bacterial overgrowth.