Skip to main content
. 2018 Oct 23;9:2419. doi: 10.3389/fimmu.2018.02419

Figure 3.

Figure 3

Combination of dietary GOS and budesonide suppresses mMCP-1 serum concentration and Th2 driving mediators in lung homogenates of HDM allergic mice. mMCP-1 (A) (pg/mL in serum) and IL-33 (B), CCL17 (C), CCL22 (D) (pg/mg protein in supernatant of lung homogenates) concentrations were measured. Statistical significance of differences was tested using post hoc Bonferroni's multiple comparisons test after One-Way ANOVA. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 compared to the HDM-contr group, +P < 0.05, ++P < 0.01, + + ++P < 0.0001, and ##P < 0.01, ###P < 0.001 compared to the PBS-contr group, n = 6 mice/group. Results are shown as mean ± SEM. PBS: PBS–sensitized and–challenged mice (white bars), HDM, HDM-sensitized and–challenged mice (gray bars). Contr, control diet; GOS, 1 w/w% GOS or 2.5 w/w% GOS diet; Bud, budesonide. Results are shown as mean ± SEM.