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. 2018 Oct 18;33(8):336–348. doi: 10.1089/cbr.2018.2494

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Copyright 2018, Mary Ann Liebert, Inc., publishers

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FIG. 4. — ⁶⁸Ga-PSMA-11 PET/CT scans of a patient with metastatic castration-resistant prostate cancer before (A) and after (B, C) receiving several cycles of ²²⁵Ac-PSMA-617, a small-molecule construct. Complete imaging response and a remarkable reduction in prostate-specific antigen, a biomarker for prostate cancer, were achieved after the final treatment, demonstrating the extraordinary potential of ²²⁵Ac for TAT. This figure was reprinted with permission from ref. 89. Copyright © 2016 by the Society of Nuclear Medicine and Molecular Imaging, Inc. TAT, targeted α therapy.