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HTS results. Histogram showing the distribution of hits from the proof-of-concept pilot screen of the LOPAC. Positive control (bortezomib 20 nM) is given in red. Negative control DMSO (1%) is given in yellow. Compounds are given in blue. A three-dimensional scatter plot of the same data (inset) is provided as an alternative view of the data. HTS, high-throughput screening; LOPAC, library of pharmacologically active compounds.
