Figure 2.

Lyz-GRP78^−/− mice become obese during 9 wk of high-fat feeding without alteration in energy balance. A) Total body weight and whole-body fat mass and lean mass of WT and Lyz-GRP78^−/− mice that were fed HFD for 9 wk (n = 5–8/group). B) Representative image of epidydimal fat pad in WT and Lyz-GRP78^−/− mice that were fed HFD for 16 wk. C) Food intake, physical activity, and energy expenditure of WT and Lyz-GRP78^−/− mice that were fed HFD for 10 wk measured by metabolic cages (n = 6 mice/group).