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. Author manuscript; available in PMC: 2018 Oct 30.
Published in final edited form as: Pflugers Arch. 2008 Oct 22;457(6):1253–1263. doi: 10.1007/s00424-008-0600-8

FIGURE 1.

FIGURE 1

Sodium channel activation was not altered by co-expression of wild-type or mutant sodium channel β1 subunits. Sodium currents were elicited by a series of voltage steps from a holding potential of −120 mV to voltages ranging from −75 to +75 mV. (A) Representative current traces from cells expressing Nav1.4 α-subunit alone (α, ○); α plus wild-type β1 (α + β1, ■); α plus β1 N-terminal mutant C121W (α + β1/C121W, ∇); and α plus β1 C-terminal deletion (α +β1/CTdel, ▲). (B) Normalized peal I-V curves show that the voltage-dependence of activation was not affected by coexpression of wild-type or mutant β1 subunits.