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. Author manuscript; available in PMC: 2018 Oct 30.
Published in final edited form as: Dev Cell. 2018 Feb 5;44(3):284–296. doi: 10.1016/j.devcel.2018.01.009

Figure 3. Leg Folding by Extruding, Apoptotic Cell Forces.

Figure 3.

During Drosophila leg-joint development, extruding apoptotic cells (blue) pull their neighbors toward the basal side at the presumptive joint area by accumulating myosin II along their apical-basal axis. Neighboring cells accumulate myosin II at their apical surface, which triggers apical constriction and subsequent fold formation.