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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Hypertension. 2018 Oct;72(4):874–880. doi: 10.1161/HYPERTENSIONAHA.118.11086

Figure 4. Somatic CACNA1D mutations found in IHA adrenals.

Figure 4.

The α1 subunit of CACNA1D is shown with domains recurrently mutated in APA indicated in blue. Each line represents the location of a somatic mutation(s) detected in an APCC from an IHA case (the adjacent number indicates total number at that position in this cohort). Previously reported somatic mutations in APA are shown in red, and unreported mutations in green. In total, 77% (44/57) of the CACNA1D mutations were in the domains recurrently mutated in APA.