Table 1.
Baseline characteristics of patients with poor or acceptable outcomes after TAVR
| Poor Outcome (38.9%1) |
Acceptable Outcome (61.1%*) |
p-value | |
|---|---|---|---|
| Age (years) | 84 (79, 88) | 84 (79, 88) | 0.514 |
| Female sex | 48.4% | 49.7% | 0.202 |
| White race | 0.010 | ||
| STS mortality risk score (%) | 7.7 (5.1, 11.7) | 6.2 (4.2, 9.4) | <0.001 |
| <4% | 14.2% | 22.2% | |
| 4–8% | 38.6% | 43.9% | |
| >8% | 47.2% | 34.0% | |
| Coronary artery disease | 64.7% | 64.5% | 0.803 |
| Prior open heart surgery | 31.2% | 33.0% | 0.058 |
| Prior stroke | 13.6% | 11.0% | <0.001 |
| Peripheral arterial disease | 34.1% | 29.2% | <0.001 |
| Severe chronic lung disease | 18.1% | 10.5% | <0.001 |
| Home oxygen | 17.4% | 8.7% | <0.001 |
| Renal function | <0.001 | ||
| Dialysis dependent | 5.4% | 2.7% | |
| Creatinine ≥2.0 mg/dL without dialysis | 7.5% | 5.0% | |
| Creatinine <2.0 mg/dL | 87.2% | 92.3% | |
| Atrial fibrillation | 48.6% | 39.0% | <0.001 |
| Permanent pacemaker/ICD | 21.2% | 17.5% | <0.001 |
| LV ejection fraction | 0.004 | ||
| <30% | 7.8% | 6.5% | |
| 30–45% | 18.9% | 17.8% | |
| >45% | 73.3% | 75.8% | |
| Mean aortic gradient (mmHg) | 42 (35, 50) | 43 (36, 52) | <0.001 |
| Moderate/severe mitral regurgitation | 34.1% | 31.9% | <0.001 |
| Baseline KCCQ-OS | 32.3 (18.8, 50.5) | 43.8 (27.1, 62.5) | <0.001 |
*
Data are inverse propensity weighted to account for patients missing follow-up data
Continuous variables are presented as median (IQR) and compared using the Wilcoxon Rank Sum Test.
STS, Society of Thoracic Surgeons; ICD, implantable cardiac defibrillator; LV, left ventricular; KCCQ-OS, Kansas City Cardiomyopathy Questionnaire-overall summary score