Table 3.
Summary of already published papers regarding the interaction of NGOs with different cells
| NP | Cell line | Outcome | References |
|---|---|---|---|
|
| |||
| NGOs | Human lung cells (BEAS-2B) | Induction of apoptosis | 49 |
| NGOs and SWCNT | Human hepatoma HepG2 | Protein profile showed oxidized SWCNTs stimulated more oxidative stress than GO | 50 |
| NGOs and reduced GO | HUVEC, human osteosarcoma cell line (MG-63), and human keratinocytes cell line (HaCaT) | ROS-mediated DNA breakage in GO-treated cells | 51 |
| NGOs | HLF cells | Severe genotoxicity | 52 |
| NGOs and carboxyl | Human hepatocellular carcinoma | Both carbon NPs induced plasma | 53 |
| graphene | cell line HepG2 | membrane leakage and induction of ROS | |
| Pegylated NGOs | Human Saos-2 osteoblasts, human HepG2 hepatocytes, and murine RAW-264.7 macrophages | Different mechanisms in PEG-GOs internalization based on each cell type | 54 |
| NGOs | Colon carcinoma (Caco-2) | Biocompatible GO | 55 |
| Lead sulfide/reduced GO quantum dots | Human mononuclear blood cells | No cytotoxicity up to 200 µg/mL | 56 |
Abbreviations: GO, graphene oxide; NGO, nano graphene oxide; HUVEC, human umbilical vascular endothelial cells; NP, nanoparticle; HLF, human lung fibroblast; SWCNT, single-walled carbon nanotube.