Figure 4.

miR-184 expression is sex dependent. miRNA expression was assessed by RT-qPCR in isolated islets from male (M) and female (F) control mice (A), human islets from male and female donors (B), human islets from healthy donors and donors with T2D (C), and human islets from healthy male and female donors and male and female donors with T2D (D). Each dot represents islets from a single mouse (A) or human donor (B–D). Data are expressed as relative to the endogenous control let-7d-3p. ns, not significant. ***P < 0.001 (Student’s t test).