Table 6.

Human i.v. plasma clearance of zoniporide, O⁶-benzylguanine, zaleplon, and BIBX1382 reported in the literature.

Compound	Human Plasma Clearance (mL/min/kg)
Zoniporide	21*
O6-Benzylguanine	14.5#
Zaleplon	16§
BIBX1382	22–55¶
SGX523	N/A

^*Dalvie D, Zhang C, Chen W, et al. (2010). Drug Metab Dispos 38:641–654.

^#Dolan ME, Roy SK, Fasanmade AA, et al. (1998). J Clin Oncol 16:1803–1810.

^§Rosen AS, Fournie P, Darwish M, et al. (1999). Biopharm Drug Dispos 20:171–175.

^¶Dittrich C, Greim G, Borner M, et al. (2002). Eur J Cancer 38:1072–1080.