Key resources table.

Reagent type (species) or resource	Designation	Source or reference	Identifiers	Additional information
Genetic reagent (M. musculus)	DATIREScre	The Jackson Laboratory (www.jax.org)	MGI:3689434
Genetic reagent (M. musculus)	Gad2tm2(cre)Zjh	The Jackson Laboratory (http://www.jax.org)	MGI:4418713
Cell line (homo sapiens, human)	HEK293T	ATCC	Cat# CRL-1573
Recombinant DNA reagent	AAV9-CAG-dLight1.1	Dr. Lin Tian, University of California Davis		Patriarchi et al., 2018
Recombinant DNA reagent	AAVDJ-EF1a-DIO-GCaMP6m	Stanford Vector Core	Cat# GVVC-AAV-94
Recombinant DNA reagent	AAV8-hSyn-DIO-ChrimsonR-tdTo	UNC Vector Core
Recombinant DNA reagent	AAV5-hSyn-DIO-HM4D(Gi)-mCherry	UNC Vector Core
Recombinant DNA reagent	AAV5-EF1a-DIO-ChR2(H134R)-eYFP	UNC Vector Core
Recombinant DNA reagent	AAV5-EF1a-DIO-eArch3.0-eYFP	UNC Vector Core
Peptide, recombinant protein	CTB (Alexa FluorTM 555 Conjugate)	Invitrogen/Thermo Fisher	Cat# C34776
Peptide, recombinant protein	CTB (Alexa FluorTM 488 Conjugate)	Invitrogen/Thermo Fisher	Cat# C34775
Peptide, recombinant protein	CTB (Alexa FluorTM 647 Conjugate)	Invitrogen/Thermo Fisher	Cat# C34778
Chemical compound, drug	Diacetylmorphine (heroin)	DiaMo Narcotics GmbH	DIAPHIN
Chemical compound, drug	Citalopram	Cayman Chemical	Cat# 14572
Chemical compound, drug	Reboxetine	Tocris	Cat# 1982
Chemical compound, drug	Cocaine	University Hospital of Geneva
Antibody	Anti-cFos	Santa Cruz Biotechnology	RRID: AB_2106783	(dilution 1:5000)
Antibody	Anti-Tyrosine Hydroxylase	Sigma-Altrich	Cat# T2928	(dilution 1:500)
Antibody	Anti- GFP	Invitrogen/Thermo Fisher	Cat# 11122	(dilution 1:500)
Software, algorithm	Prism 7.02	Graphpad
Software, algorithm	MATLAB R2017a	Mathworks
Software, algorithm	Synapse	Tucker-Davis Technologies