Figure 2. Fibronectin promotes BCC adhesion and migration.
(a)Crystal violet staining of adhesion assays performed with UW_BCC_T2 and ASZ_001 on BSA, collagen I or fibronectin. Scale bars indicate 1mm.
(b) Quantification of adhesion assays shown in (a).
(c) Crystal violet staining of long-term clonogenic assays performed with UW_BCC_T2 and ASZ_001 on uncoated or fibronectin-coated plates.
(d) Timecourse and crystal violet staining of migration assays performed with UW_BCC_T2 on uncoated or fibronectin-coated plates.
(e) Timecourse and crystal violet staining of migration assays performed with ASZ_001 on uncoated or fibronectin-coated plates.
(f) Tumor cell velocity measured from migration assays performed in (d) and (e).
Scale bars indicate 100μm (unless specified). Columns and error bars represent the mean ± SD for n ≥ 3 per group. *p < 0.05, **p < 0.01 and ***p < 0.001.