Figure 7.
Anti-proliferative function of HIV-1-treated B cells. Proliferation of autologous effector cells (EC) treated with CFSE and co-cultured with not-treated (NT) or treated B cells (ratio Breg:EC of 2:1) at day 3 post co-culture. As a control, EC were also cultured alone without B cells (EC non-activated and EC activated). Average±s.e.m. of the percentage of proliferative CD4+ and CD8+ T cells measured in anti-CD3/anti-CD28-stimulated EC in the presence of B cells. Values from five different donors are shown. *P<0.05 when comparing mock-treated condition versus treated conditions and # P<0.05 when comparing activated and non-activated EC cells.