Table 3.
CD6 total patient haplotype frequency distribution and further analysis between patients displaying ‘mild’ and ‘severe’ Ps (top), as well as low (⩽7) vs high PASI scores (bottom)
| Rs17824933 | Rs11230563 | Rs12360861 | % | OR (95% CI) | P-value | Adj.a ORa (95% CI) | Adj.a P-value |
|---|---|---|---|---|---|---|---|
| C | C | G | 33.0 | ||||
| G | C | G | 24.2 | 1.31 (0.82–2.08) | 0.26 | 1.12 (0.68–1.84) | 0.660 |
| C | T | A | 23.6 | 0.61 (0.38–0.99) | 0.046 | 0.62 (0.36–1.05) | 0.074 |
| C | T | G | 19.2 | 0.99 (0.61–1.60) | 0.95 | 0.77 (0.45–1.31) | 0.330 |
| C | C | G | 32.5 | ||||
| G | C | G | 24.6 | 0.04 (−0.12 to 0.21) | 0.59 | 0.01 (−0.16 to 0.17) | 0.930 |
| C | T | A | 23.9 | −0.23 (−0.41 to 0.06) | 0.008 | −0.2 (−0.37 to 0.02) | 0.033 |
| C | T | G | 19.0 | 0.64 (−0.36 to 1.64) | 0.013 | −0.27 (−0.45 to 0.09) | 0.003 |
Abbreviations: Adj., adjusted; CI, confidence interval; OR, odds ratio; PASI, Psoriasis Area and Severity Index.
aMultivariate analysis adjusted by onset of disease, arthropathy occurrence, gender and disease length.