Table 3.
Clinical trials of electrospun scaffolds.
| Study | Status | Condition/disease | Aim | Number of participants | Scaffold | Results |
|---|---|---|---|---|---|---|
| Experimental study of the vascular prosthesis manufactured by electrospinning (NCT02255188) | Completed | Arterial occlusive disease | Determination of the safety of electrospun vascular grafts for the development of thrombosis. | 120 | PCL grafts; PCL/gelatin grafts; PLGA/PCL/gelatin grafts; Nylon 6 grafts. | Not currently available |
| EktoTherix™ regenerative tissue scaffold for repair of surgical excision wounds (NCT02409628) | Completed | Non-melanoma skin cancer; Basal cell carcinoma; Squamous cell carcinoma | Assessment of the safety and performance of EktoTherix™ Tissue Repair Scaffold for the treatment of full-thickness, dermatologic wounds due to the surgical removal of non-melanoma skin cancers. | 12 | EktoTherix™ Tissue Repair Scaffold: | Not currently available |
| Clinical trial for the treatment of diabetic foot ulcers using a nitric oxide releasing patch: PATHON | Completed | Diabetic foot | Evaluation of the effectiveness and safety of nitric oxide releasing wound dressings for the treatment of diabetic foot ulcers. | 100 | Multilayer polymeric transdermal patch with a continuous release of nitric oxide (polyurethane-based fibers). | Not currently available |
| Controlled nitric oxide releasing patch vs. meglumine antimoniate in the treatment of cutaneous Leishmaniasis | Terminated | Cutaneous Leishmaniasis | Evaluation of the effectiveness of a nitric oxide topical donor for the treatment of cutaneous leishmaniasis. | 178 | Multilayer polymeric transdermal patch with a continuous release of nitric oxide (polyurethane-based fibers). | Not currently available |
The data are obtained from ClinicalTrials.gov, a resource provided by the U.S. National Library of Medicine (Accessed on September 2018).