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. 2018 Oct 24;6:155. doi: 10.3389/fbioe.2018.00155

Table 3.

Clinical trials of electrospun scaffolds.

Study Status Condition/disease Aim Number of participants Scaffold Results
Experimental study of the vascular prosthesis manufactured by electrospinning (NCT02255188) Completed Arterial occlusive disease Determination of the safety of electrospun vascular grafts for the development of thrombosis. 120 PCL grafts; PCL/gelatin grafts; PLGA/PCL/gelatin grafts; Nylon 6 grafts. Not currently available
EktoTherix™ regenerative tissue scaffold for repair of surgical excision wounds (NCT02409628) Completed Non-melanoma skin cancer; Basal cell carcinoma; Squamous cell carcinoma Assessment of the safety and performance of EktoTherix™ Tissue Repair Scaffold for the treatment of full-thickness, dermatologic wounds due to the surgical removal of non-melanoma skin cancers. 12 EktoTherix™ Tissue Repair Scaffold: Not currently available
Clinical trial for the treatment of diabetic foot ulcers using a nitric oxide releasing patch: PATHON Completed Diabetic foot Evaluation of the effectiveness and safety of nitric oxide releasing wound dressings for the treatment of diabetic foot ulcers. 100 Multilayer polymeric transdermal patch with a continuous release of nitric oxide (polyurethane-based fibers). Not currently available
Controlled nitric oxide releasing patch vs. meglumine antimoniate in the treatment of cutaneous Leishmaniasis Terminated Cutaneous Leishmaniasis Evaluation of the effectiveness of a nitric oxide topical donor for the treatment of cutaneous leishmaniasis. 178 Multilayer polymeric transdermal patch with a continuous release of nitric oxide (polyurethane-based fibers). Not currently available

The data are obtained from ClinicalTrials.gov, a resource provided by the U.S. National Library of Medicine (Accessed on September 2018).