Table 4.
Autoantibodies against complement components.
| Analyses | Anti-C1q1 | Anti-C1q2 | Anti-C1-INH | Anti-FH | C3NeF | C4NeF |
|---|---|---|---|---|---|---|
| SLE, Sjögrens | + | – | (+) | – | –/(+) | – |
| Hypocomplementary urticarial vasculitis | + | + | – | – | – | – |
| C3GN | –/+ | – | – | –/(+) | + | + |
| aHUS | – | – | – | + | – | – |
| HAE Type I, Type II | – | – | – | – | – | – |
| AAE | – | – | + | – | – | – |
Anti-C1q1, antibodies against native C1q; Anti-C1q2, antibodies against reduced chains of C1q; C3NeF, C3 nephritic factor; C4NeF, C4 nephritic factor; SLE, systemic lupus erythematosus; C3GN, C3 glomerulonephritis; aHUS, atypical haemolytic uremic syndrome; PSGN, post-streptococcal glomerulonephritis; HAE, hereditary angioedema, AAE, acquired angioedema.