Table 2.
Neurological complications in young infants with acute bacterial meningitis.
| Alive and discharge with no neurological deterioration (n = 47) | Death and/or neurological deterioration (n = 38) | P-value | |
|---|---|---|---|
| Any neurological complications | 29 (61.7) | 36 (94.7) | <0.001 |
| Seizure | 18 (38.3) | 29 (76.3) | <0.001 |
| Subdural effusion | 18 (38.3) | 22 (57.9) | 0.072 |
| Increased intracranial pressure | 7 (14.9) | 17 (44.7) | <0.001 |
| Ventriculomegaly | 12 (25.5) | 23 (60.5) | 0.001 |
| Hydrocephalus | 3 (6.4) | 13 (34.2) | 0.001 |
| Encephalomalacia | 1 (2.1) | 8 (21.1) | 0.009 |
| Subependymal hemorrhage | 5 (10.6) | 3 (7.9) | 0.726 |
| Ventriculitis | 5 (10.6) | 8 (21.1) | 0.153 |
| Periventricular leukomalacia | 6 (12.8) | 4 (10.5) | 0.512 |
| Infarction | 2 (4.3) | 6 (15.8) | 0.075 |
| Subdural empyema or abscess | 5 (10.6) | 13 (34.2) | 0.015 |
| Brain atrophy | 0 (0) | 2 (5.3) | 0.197 |
| Total antibiotic duration (days), median (IQR) | 21.0 (17.0–28.0) | 28.5 (21.0–45.8) | 0.004 |
IQR, interquartile range.