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. 2018 Oct 30;8:16025. doi: 10.1038/s41598-018-34270-5

Table 2.

Expected ratio of homozygous cleaved alleles calculated by a cleavage activity based on genotypes of PC12 cells.

In-frame Frameshift
In-frame (1–0.8)2 = 0.04 0.8 × (1–0.8) = 0.16
Frameshift 0.8 × (1–0.8) = 0.16 0.802 = 0.64