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Lubricant use is associated with shifts in rectal microbiota composition.
Mean relative abundance of the top 10 most abundant genera in the rectal mucosa before and after study product use stratified by study arm: Lube only, PrEP only, or PrEP and Lube use for seven days (a). Change in mean relative abundance before and after study product use in terms of lubricant and PrEP use for the top 10 genera were examined by linear regression modelling (b). PrEP, pre‐exposure prophylaxis.
