Table 2.

The association of single nucleotide polymorphisms and visual field progression.

Gene	SNP	Chr	Position	MA	MAF	HWE	OR (95%CI)	P_logit†	P_cox‡
TGFBR3-CDC7	rs1192415	1	91611540	G	0.165	0.165	1.37 (0.93–2.01)	0.108	0.277
TMCO1	rs4656461	1	165717968	G	0.018	0.130	2.25 (0.83–6.08)	0.112	0.326
TMCO1	rs7555523	1	165749742	C	0.018	0.130	2.24 (0.82–6.06)	0.114	0.338
CDKN2B-AS1	rs1063192	9	22003368	G	0.163	0.862	1.18 (0.80–1.74)	0.399	0.216
CDKN2B-AS1	rs523096	9	22019130	G	0.088	0.128	1.35 (0.83–2.21)	0.223	0.190
CDKN2B-AS1	rs7049105	9	22028802	A	0.319	0.511	1.18 (0.87–1.61)	0.277	0.249
CDKN2B-AS1	rs2157719	9	22033367	G	0.084	0.217	1.44 (0.87–2.36)	0.156	0.172
CDKN2B-AS1	rs4977756	9	22068653	G	0.194	1.000	1.33 (0.93–1.91)	0.119	0.070
CDKN2B-AS1	rs10116277	9	22081398	G	0.270	0.545	1.17 (0.85–1.62)	0.344	0.774
ATOH7	rs7916697	10	68232096	A	0.377	0.479	1.28 (0.96–1.71)	0.099	0.126
ATOH7	rs1900004	10	68241124	A	0.377	0.614	1.24 (0.93–1.67)	0.147	0.190
ATOH7	rs3858145	10	68252081	G	0.376	0.919	1.28 (0.95–1.72)	0.107	0.067
SIX1/SIX6	rs33912345	14	60509819	A	0.180	0.520	1.08 (0.75–1.56)	0.673	0.579
SIX1/SIX6	rs10483727	14	60606157	C	0.184	0.525	1.12 (0.78–1.61)	0.533	0.567

Chr, chromosome; MA, minor allele; MAF, minor allele frequency; HWE, Hardy–Weinberg equilibrium; OR, odds ratio; CI, confidence interval. The position of each SNP was referred to NCBI build GRCh38.p7. ^†P_logit values were calculated by logistic regression adjusted with age, gender, baseline MD, follow-up IOP, CCT, AL from comparison of allele frequencies between progress group and non-progress group.^‡P_cox values were calculated by cox regression adjusted with age, gender, baseline MD, follow-up IOP, CCT, AL from comparison of patients with 1 or 2 risk alleles versus with 0 risk allele.