Table 1.

Comparison of body, fat and organ weights.

Groups	normal	HFD	metformin	metformin + HCE	HCE
Body weight gain (g/week)	0.48 ± 0.07	1.62 ± 0.22##	1.40 ± 0.23	1.04 ± 0.46**	1.22 ± 0.37*
Food intake (g/week)	16.9 ± 0.8	17.4 ± 0.8	15.6 ± 0.8**	16.5 ± 0.8*	16.4 ± 0.7*
Food efficiency ratio	0.028	0.094	0.085	0.059	0.072
Abdominal fat (g)	0.29 ± 0.05	1.51 ± 0.09##	1.23 ± 0.31*	0.74 ± 0.36**	1.12 ± 0.23**
Perirenal fat (g)	0.29 ± 0.11	0.99 ± 0.09##	0.98 ± 0.14	0.80 ± 0.15*	0.83 ± 0.14*
Epididymal fat (g)	0.86 ± 0.21	1.93 ± 0.29	2.31 ± 0.46	2.20 ± 0.38	2.20 ± 0.43
Total fat (g)	1.49 ± 0.37	4.40 ± 0.38#	4.52 ± 0.47	3.76 ± 0.80*	4.14 ± 0.53
Liver weight (g)	0.93 ± 0.08	1.86 ± 0.15##	1.40 ± 0.28**	1.16 ± 0.33**	1.24 ± 0.21**
Kidney weight (g)	0.32 ± 0.02	0.39 ± 0.03##	0.34 ± 0.03**	0.36 ± 0.02*	0.34 ± 0.03**

TC, total cholesterol; HDL, high density lipoprotein; TG, triglyceride. Data were expressed as Mean ± SD, different letters indicate significantly different at measured by One-Way ANOVA followed by LSD (P < 0.05, n = 8).

^#P < 0.05,

^##P < 0.01 compared to the normal group;

^*P < 0.05,

^**P < 0.01 compared to the HFD group.