Table 2.

Comparison of serum biochemistry parameters.

Groups	normal	HFD	metformin	metformin + HCE	HCE
TG (mg/dL)	159 ± 38	182 ± 28	195 ± 26	154 ± 18*	176 ± 32
TC (mg/dL)	128 ± 15	187 ± 24##	177 ± 11	155 ± 21**	173 ± 33*
HDL (mg/dL)	27.19 ± 4.72	18.67 ± 2.29##	20.42 ± 1.45	22.95 ± 2.04**	17.66 ± 1.99
AST	24.88 ± 8.62	35.87 ± 6.29#	32.24 ± 7.96	22.87 ± 4.81**	28.49 ± 7.42
ALT	6.43 ± 3.15	23.73 ± 4.90##	14.56 ± 9.19*	6.39 ± 3.97**	9.82 ± 5.78**

TC, total cholesterol; HDL, high density lipoprotein; TG, triglyceride. Data were expressed as Mean ± SD, different letters indicate significantly different at measured by One-Way ANOVA followed by LSD (P < 0.05, n = 7).

^#P < 0.05,

^##P < 0.01 compared to the normal group;

^*P < 0.05,

^**P < 0.01 compared to the HFD group