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. 2018 Oct 24;9:468. doi: 10.3389/fpsyt.2018.00468

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Copyright © 2018 Zeng, Xie, Zhang, Zhong, Liu and Hao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PFC GABA-Aα5 histone H3K4 trimethylation increased in offspring with an alcohol genetic background. ChIP-PCR was used to detect the relative level of GABA-Aα5 histone H3K9 acetylation and H3K4 trimethylation in the PFC of offspring. (A) The relative level of GABA-Aα5 histone H3K9 acetylation in the PFC of offspring. (B) The relative level of GABA-Aα5 histone H3K4 trimethylation in the PFC of offspring. The data are expressed as the mean ± SD (n = 6). ^*p < 0.05 vs. MSFS, two-way ANOVA.