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. 2018 Oct 30;6:30. doi: 10.1186/s40364-018-0144-9

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 12 — Immunoblot showing caspase-6 downregulation with siRNA. Primary human ovarian surface epithelial cells (HOSE), A2780 and OVCAR5 cell lines were transfected with siRNA for 72 h before cell lysates were collected for western blot analysis. HOSE cells displayed prominent levels of lamin A/C and low level of caspase-6 expression in contrast to cancer cell lines A2780 and OVCAR5. Caspase-6 downregulation was observed in A2780 and OVCAR5 cell lines but no effect was observed on lamin A/C expression