Table 1.
Clinical characteristics of patients diagnosed with stage III, grade III, serous ovarian epithelial cancer at Princess Margaret by length of survival
| Covariate | Full Sample (n = 41) | LT (n = 20) | ST (n = 21) | p value |
|---|---|---|---|---|
| Number of patients | 41 | 20 | 21 | |
| Stage III, HGSOC | 41 (100) | 20 (49) | 21 (51) | |
| Overall Survival | < 0.001 | |||
| < 6 months | 0 (0) | 0 (0) | 0 (0) | |
| 6–12 months | 2 (5) | 0 (0) | 4 (19) | |
| 12–24 months | 19 (46) | 0 (0) | 17 (81) | |
| > 24 months | 20 (49) | 20 (100) | 0 (0) | |
| Age at diagnosis | 0.024 | |||
| Mean (sd) | 59 (9.3) | 56.1 (9.4) | 61.7 (8.7) | 0.024 |
| Median (min,max) | 57 (40,84) | 55.5 (40,84) | 59 (47,76) | |
| Residual disease | 0.012 | |||
| No | 18 (44) | 13 (65) | 5 (24) | |
| Yes | 23 (56) | 7 (35) | 16 (76) | |
| Disease recurrence | < 0.001 | |||
| No | 17 (41) | 17 (85) | 0 (0) | |
| Yes | 24 (59) | 3 (15) | 21 (100) | |
| Number of disease recurrence | < 0.001 | |||
| 0 | 17 (41) | 17 (85) | 0 (0) | |
| 1 | 15 (37) | 1 (5) | 14 (67) | |
| 2 | 7 (17) | 1 (5) | 6 (29) | |
| > 2 | 2 (5) | 1 (5) | 1 (5) | |
| CA125 at diagnosis | 0.39 | |||
| Mean (sd) | 1207 (1781.6) | 870.4 (863.1) | 1491 (2277.9) | |
| Median (min,max) | 475 (67,9162) | 585 (67,2700) | 399 (184,9162) | |
| Missing | 6 | 4 | 2 | |
| CA125 at diagnosis rate | 0.41 | |||
| Unknown | 6 (15) | 4 (20) | 2 (10) | |
| 0–35 U/mL | 0 (0) | 0 (0) | 0 (0) | |
| > 35 U/mL | 35 (85) | 16 (80) | 19 (90) | |
| CA125 post-surgery | < 0.001 | |||
| Mean (sd) | 421 (932.4) | 63.9 (74.8) | 799.1 (1243.4) | |
| Median (min,max) | 121 (7,4712) | 33 (7299) | 296 (53,4712) | |
| Missing | 6 | 2 | 4 | |
| CA125 post-surgery rate | < 0.001 | |||
| Unknown | 6 (15) | 2 (10) | 4 (19) | |
| 0–35 U/mL | 9 (22) | 9 (45) | 0 (0) | |
| > 35 U/mL | 26 (63) | 9 (45) | 17 (81) | |
| CA125 post chemotherapy | < 0.001 | |||
| Mean (sd) | 656.4 (3772.9) | 4.6 (2.1) | 1308 (5325.7) | |
| Median (min,max) | 6.5 (2,23,290) | 4 (2,10) | 18 (4, 23,287) | |
| Missing | 3 | 1 | 2 | |
| CA125 post chemotherapy rate | 0.0063 | |||
| Unknown | 3 (7) | 1 (5) | 2 (10) | |
| 0–35 U/mL | 31 (76) | 19 (95) | 12 (57) | |
| > 35 U/mL | 7 (17) | 0 (0) | 7 (33) | |