Table 3. Expression of TGF-β target genes categorized by biological function.

Numbers in parenthesis next to the name of each category indicates the number of identified, related genes and shown in the right column.

Cancer (44)	ADAM19, AGPAT2, ARRDC2, ARRDC4, ASCL2, BCL9L, CD151, CIB1, CREG1, DNAJA2, DNMT1, ECHDC3, EGFL7, FAM110A, FAM65B, FCGR2B, FRRS1, GALC, HMGN1, IKZF2, IL34, IMPACT, ITGA5, LGALS12, LRIG1, NKD1, NOV, OLIG1, PHB, PIK3R3, POLR2J3, RPAP3, SERINC2, SMN1, SNRPF, SULT1A3, THBS1, TMEM2, TNK2, TUBA1A, TUBB8, UBASH3B, VDAC1, WIZ
Carbohydrate metabolism (34)	ADORA2B, ADRB2, ALDH6A1, AREG, BLMH, CASP3, CCL4L1, CYP51A1, EMR3, EVI2B, FAS, GNG2, GPR65, GPR153, GPR174, HOMER3, HRH4, ICAM1, INTS7, OPRL1, OSM, P2RY13, P2RY14, PTGER4, PYGL, S1PR2, SORD, SUCNR1, TMBIM1, TSEN34, VEGFA, VIM, YWHAH, ZNF124
Cardiovascular disease (20)	ACP5, ARID5A, ARL4C, CABIN1, CNPY4, MARCH3, MRPS6, MT1X, NUDT4, NUDT5, PSTPIP2, PTPN22, PTPRJ, RGS2, RGS3, SLC18A2, SRXN1, STARD10, TRPC6, XK
Cell cycle (29)	AHR, ARHGEF19, ATP10D, BOLA2B, CDCA4, E2F1, FAM101B, FAM98A, FHOD1, HAUS8, HELB, HMGA1, IER2, IER3, KCTD5, MICALL1 NIN, NLRC3, NXT1,ODC1, PAPSS1, PDZD11, SIGMAR1, SP4, SPAG1, STAMBPL1, STK39, TBC1D8, TMEM55A
Cell death and survival (77)	ADORA2B, ADRB2, ALDH6A1, AREG, ASMTL, BLMH, BIR3, C9orf40, CASP3, CCL4L1, CD84, CD200R1, CYP51A1, DUSP6, EEPD1, EFEMP2, EHD4, EMR3, ENC1, ENO3, ETS2, FAM127B, FAM65A, FAM78A, FAS, FBN1, FCGR3A, FH, GAS7, GNG2, HAS1, HIPK2, HMOX1, ICAM1, IDO1, IL18RAP, IL1RL1, IL5RA, INPP1, IRAK1, IRAK2, IRF5, KLF10, LAT2, LDHA, LILRB2, LIPA, LMO7, LYZ, METTL7A, MSTO1, MXRA7, MYB, MYD88, MTHFD2, PM20D2, PMAIP1, PRDM1, PRKD3, PTPRE, PXMP4, QPCT, RFX1, RFX2, SLC39A3, TGFBR1, TIAM2, TNFSF13B, TNFSF14, TTF2, UBA5, VEGFA, VIM, YWHAH, ZBTB4, ZC3H12A, ZNF124
Cell-To-Cell signaling and interaction (15)	ACP6, UBR7, CD151, CIB1, CREG1, FAM117A, FCGR2B, ITGA5, LRIG1, MCCC1, NOV, PIK3R3, RDH11, THBS1, TNK2
Cellular assembly and Organization (44)	ACP6, ANXA1, ARHGEF19, ARL6IP6, ATP10D, BOLA2B, C12orf65, UBR7, C7orf25, C9orf50, C9orf142, CCDC85B, DAPK1, FAM101B, FAM117A, FAM98A, FMNL3, GADD45G, GZF1, HAUS8, HRASLS5, KCTD5, LIMK1, MCCC1, MICALL1, NFAM1, NIN, NLRC3, NXT1, PAPSS1, PTPRCAP, RABEPK, RASSF7, RD3, RDH11, RDX, RHOF, RHOQ, SFMBT2, SPAG1, STAMBPL1, TCP11L1, TMEM55A, ZSCAN16
Cellular compromise (12)	ANXA1, DAPK1, DAPP1, GADD45G, LIMK1, NFAM1, PTPRCAP, RABEPK, RASSF7, RDX, RHOF, RHOQ
Cellular development (93)	ACOT7, AMICA1, ANKRD37, ANKRD55, BIR3, BLMH, C3AR1, CD84, CD200R1, CD83, CISH, CLC, CYP51A1, DUSP6, EFEMP2, EHD4, EMR3, ENC1, ENO3, EPOR, ETS2, FAS, FBN1, FCGR3A, FH, FLVCR1, GRASP, HAS1, HIPK2, HMOX1, IDO1, IER2, IL18RAP, IL1RL1, IL5RA, INPP1, IPCEF1, IRAK1, IRAK2, IRF5, KCTD11, KCTD15, KLF10, LAT2, LDHA, LILRB2, LIPA, LMO7, LYL1, LYZ, MAPK13, MARCH1, MEGF9, METTL7A, MTHFD2, MYB, MYD88, NAMPT, NFKB1, NKD1, NUCB2, OLIG1, OLIG2, PGM2, PIM1, PMAIP1, PRDM1, PRKD3, PTPRE, QPCT, RFX1, RFX2, SGPP1, SIRPD, SNRNP25, ST6GALNAC6, TGFBR1, TIAM2, TKTL1, TNFSF13B, TNFSF14, TRIM36, TRIM5, TRIOBP, TSPAN14, TTF2, UBA5, UGT2B28, ZBTB4, ZC3H12A, ZFP36, ZNF219, ZNF524
Cellular function and Maintenance (94)	ACOT7, ACP6, AJAP1, AMICA1, ANKRD37, ANKRD55, ANXA1, AP4B1, ARHGEF19, ATP10D, BBC3, BLMH, BOLA2B, C14orf142, C3AR1, CACNG6, CACNG8, CARD9, CBLB, CD244, CD48, CD69, CD84, CD200R1, CERK, CLC, CYP51A1, DAPK1, DAPP1, DUSP6, EFEMP2, EHD4, EMR3, ENO3, FAM101B, FAM117A, FAM98A, FAS, FBN1, FYB, GADD45G, GRASP, GRN, HAUS8, HIPK2, IDO1, INPP1, KCTD15, KCTD5, KLF10, LAT2, LIMK1, LTC4S, MCCC1, MICALL1, MPHOSPH6, MYB, NFAM1, NFKBIE, NLRC3, NXT1, PAPSS1, PLK3, PTPRCAP, QPCT, RABEPK, RASSF7, RDH11, RDX, RHOF, RHOQ, RIPK2, SDCBP2, SIRPD, SLAMF6, SLC1A4, SLC7A5, SNAI3, SPAG1, SSBP4, STAMBPL1, STK17B, TBC1D2, TBC1D9B, TGFBR1, TIAM2, TMEM55A, TRIM5, TRIM8, TSPAN14, TTF2, UAP1L1, ZBTB4, ZNF524
Cellular growth and Proliferation (62)	AHR, BIR3, CDCA4, E2F1, ECHDC3, ENC1, ETS2, FCGR3A, FH, FHOD1, FLVCR1, GAS7, HAS1, HELB, HMGA1, HMOX1, IER2, IER3, IL18RAP, IL1RL1, IL5RA, IPCEF1, IRAK1, IRAK2, KCTD11, IRF5, LDHA, LILRB2, LIPA, LMO7, LYZ, MEGF9, METTL7A, MTHFD2, MYD88, NAMPT, NKD1, NUCB2,ODC1, OLIG1, OLIG2, PDZD11, PGM2, PMAIP1, PRKD3, PTPRE, RFX1, RFX2, SGPP1, SIGMAR1, SNRNP25, SP4, ST6GALNAC6, STK39, TBC1D8, TKTL1, TNFSF13B, TNFSF14, UBA5, UGT2B28, ZC3H12A, ZNF219
Cellular movement (15)	BCL9L, EVI2B, ECHDC3, FAM110A, FAM65B, FRRS1, GALC, IKZF2, IL34, IMPACT, NKD1, OLIG1, SERINC2, TMEM2, UBASH3B
Developmental disorder (10)	CCDC146, FBXL14, FRMD4B, MUM1, MYCT1, PPIF, SAMD1, SCAMP4, SLC7A5, TMEM60
Digestive system development and function (21)	ACAT2, ALAS1, BCOR, DDX21, FASN, HES1, HES6, HLX, ID2, JDP2, JUN, KDM2B, KLF6, LIN52, NR2F6, ORC1L, SLC20A1, TFDP2, UBTF, VKORC1L1, YEATS4
Embryonic development (21)	ACAT2, ALAS1, BCOR, DDX21, FASN, HES1, HES6, HLX, ID2, JDP2, JUN, KDM2B, KLF6, LIN52, NR2F6, ORC1L, SLC20A1, TFDP2, UBTF, VKORC1L1, YEATS4
Endocrine system disorders (14)	ASMTL, C9orf40, EEPD1, FAM127B, FAM65A, FAM78A, MSTO1, MXRA7, NAPRT1, P2RY8, PHTF2, PM20D2, PXMP4, SLC39A3
Gene expression (29)	AJAP1, ASMTL, C3AR1, C9orf40, CACUL1, CACNG6, CACNG8, CARD9, EEPD1, FAM127B, FAM65A, FAM78A, MPHOSPH6, MSTO1, MXRA7, NAPRT1, P2RY8, PHTF2, PM20D2, PXMP4, SDCBP2, SLAMF6, SLC1A4, SLC39A3, SNAI3, SSBP4, TBC1D2, TBC1D9B, UAP1L1
Hair and skin development and function (1)	MPZL3
Hematological disease (20)	ACP5, ARID5A, ARL4C, CABIN1, CNPY4, MARCH3, MRPS6, MT1X, NUDT4, NUDT5, PSTPIP2, PTPN22, PTPRJ, RGS2, RGS3, SLC18A2, SRXN1, STARD10, TRPC6, XK
Hematological system development and function (21)	ACOT7, AMICA1, ANKRD37, ANKRD55, AP4B1, BBC3, C3AR1, CARD9, CBLB, CD48, CD69, CD244, CD83, CERK, CISH, CLC, EMR3, EPOR, FYB, GRASP, GRN, KCTD15, LTC4S, LYL1, MAPK13, MARCH1, NFKB1, NFKBIE, PIM1, PLK3, RIPK2, SIRPD, SLC7A5, STK17B, TRIM36, TRIOBP, TRIM5, TRIM8, TSPAN14, ZFP36, ZNF524
Hematopoiesis (11)	CD83, CISH, EPOR, LYL1, MAPK13, MARCH1, NFKB1, PIM1, TRIM36, TRIOBP, ZFP36
Hepatic system development and function (21)	ACAT2, ALAS1, BCOR, DDX21, FASN, HES1, HES6, HLX, ID2, JDP2, JUN, KDM2B, KLF6, LIN52, NR2F6, ORC1, SLC20A1, TFDP2, UBTF, VKORC1L1, YEATS4
Hereditary disorder (20)	ACP5, ARID5A, ARL4C, CABIN1, CNPY4, MARCH3, MRPS6, MT1X, NUDT4, NUDT5, PSTPIP2, PTPN22, PTPRJ, RGS2, RGS3, SLC18A2, SRXN1, STARD10, TRPC6, XK
Molecular transport (21)	BLMH, CYP51A1, EMR3, FAS, GPR65, GPR153, GPR174, HOMER3, HRH4, INTS7, OPRL1, OSM, P2RY13, P2RY14, PTGER4, PYGL, S1PR2, SORD, SUCNR1, TMBIM1, TSEN34
Nervous system development and function (14)	ARL6IP6, C12orf65, C7orf25, NTMT1, UBR7, CCDC85B, FMNL3, GZF1, HRASLS5, RASSF7, RD3, SFMBT2, TCP11L1, ZSCAN16
Organismal injury and abonormalities (29)	ADAM19, AGPAT2, ARRDC2, ARRDC4, ASCL2, CCDC146, DNAJA2, DNMT1, EGFL7, FBXL14, FRMD4B, HMGN1, LGALS12, MUM1, MYCT1, PHB, POLR2J3, PPIF, RPAP3, SAMD1, SCAMP4, SLC7A5, SMN1, SNRPF, SULT1A3, TMEM60, TUBB8, VDAC1, WIZ
Reproductive system development and function (13)	ENC1, FLVCR1, IER2, IPCEF1, KCTD11, MEGF9, NUCB2, PGM2, SNRNP25, ST6GALNAC6, TKTL1, UGT2B28, ZNF219
Reproductive system disease (10)	CCDC146, FBXL14, FRMD4B, MUM1, MYCT1, PPIF, SAMD1, SCAMP4, SLC7A5, TMEM60
Skeletal and muscular Disorders (15)	AJAP1, C3AR1, C5AR2, CACNG6, CACNG8, CARD9, MPHOSPH6, SDCBP2, SLAMF6, SLC1A4, SNAI3, SSBP4, TBC1D2, TBC1D9B, UAP1L1
Small molecule biochemistry (33)	ADORA2B, ADRB2, ALDH6A1, AREG, BLMH, CASP3, CCL4L1, CYP51A1, EMR3, FAS, GNG2, GPR65, GPR153, GPR174, HOMER3, HRH4, ICAM1, INTS7, OPRL1, OSM, P2RY13, P2RY14, PTGER4, PYGL, S1PR2, SORD, SUCNR1, TMBIM1, TSEN34, VEGFA, VIM, YWHAH, ZNF124
Tissue development (35)	AHR, BCL9L, CD151, CDCA4, CIB1, E2F1, FAM110A, FAM65B, FCGR2B, FHOD1, FRRS1, GALC, HELB, HMGA1, IER2, IER3, IKZF2, IL34, IMPACT, ITGA5, LRIG1, NKD1, NOV, ODC1, PDZD11, PIK3R3, SERINC2, SIGMAR1, SP4, STK39, TBC1D8, THBS1, TMEM2, TNK2, UBASH3B
Tissue morphology (52)	ADAM19, AGPAT2, AP4B1, ARL6IP6, ARRDC2, ARRDC4, ASCL2, BBC3, C12orf65, C7orf25, NTMT1, C9orf142, CARD9, CBLB, CCDC85B, CD48, CD69, CD244, CEDKN1A, CERK, DNAJA2, DNMT1, EGFL7, FMNL3, FYB, GZF1, GRN, HMGN1, HRASLS5, LGALS12, LTC4S, NFKBIE, PHB, PLK3, POLR2J3, RASSF7, RD3, RIPK2, RPAP3, SFMBT2, SLC7A5, SMN1, SNRPF, STK17B, SULT1A3, TCP11L1, TRIM8, TUBA1A, TUBB8, VDAC1, WIZ, ZSCAN16