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. 2018 Oct 31;8:16081. doi: 10.1038/s41598-018-34330-w

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Numbers of DEGs those were either common or specific for each time point (1 h, 3 h, 5 h) in each sponge species upon MAMP treatment. Within each time point, DEGs were identified by comparing gene expression levels in MAMP relative to control treatment and according to the defined threshold FDR p-value < 0.005 and log2|FC| ≥ 2 expression, as calculated in edgeR. “Up-regulated” and “down-regulated” refers to genes with higher and lower expression in MAMP than in control treatment, respectively.