Table 5.

Annotated DEGs (FDR p-value < 0.005) in D. avara.

Gene Description	Gene IDs	Time	LogFC	FDR
Recognition/cell adhesion/protein binding
Fibrinogen	TR120914_c5_g8	1 h	11.2	8.3 e-5
Ig superfamily	TR137811_c2_g1	5 h	10.0	0.001
Ank repeats and ion transport domain-containing gene	TR142305_c0_g2	1 h	9.2	0.004
Gene containing Ig domains and a CARD domain	TR154561_c0_g1	1 h	10.5	4.3 e-4
Signalling cascade
DEATH domain-containing gene (CRADD-like)	TR165768_c5_g2	1 h	11.2	8.3 e-5
Serine/Threonine protein receptor-like kinase	TR23945_c0_g1	1 h	10.2	4.5 e-4
TRAF2	TR153933_c4_g2	1 h	9.8	8.3 e-5
Kelch motif containing gene	TR146020_c0_g1	3 h; 5 h	−12.6; − 13.5	4.6 e-5; 2.4 e-7
Lipid-mediated signalling
Phospholipase D	TR123257_c3_g1	1 h	9.6	0.002
Extracellular matrix
Collagen	TR287787_c0_g1	1 h; 3 h; 5 h	−11.0; −12.1; −11.6	0.003; 1.4 e-4; 1.1 e-4
Chaperone
Heat shock protein 70	TR98706_c0_g1	3 h	12.2	2.6 e-4
DNA regulation
Histone	TR1159_c0_g1	3 h	−7.1	0.004

Gene description is based on domain annotation and/or blast results. Supplementary Information provides full information on annotation (including e-values) (Supplementary Table S7) and full DGE results (here we provide rounded log₂ fold change and FDR p-values, full values are reported in Supplementary Table S4). Log FC: log₂ (fold change). Positive values of Log FC denote up-regulated genes and are coloured in orange; negative values of log FC denote down-regulated genes and are coloured in blue. FDR: false discovery rate-corrected p-value. Ig: immunoglobulin; Ank: Ankyrin; CARD: caspase recruitment domain.