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. 2018 Oct 31;8:16094. doi: 10.1038/s41598-018-34409-4

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Targets for the four selected miRNAs include those for kinases and gene regulation and appear in a number of functional classes. (A) Cytoscape representation of miRNA-target network based on data and text mining. Targets containing UniProt keyword kinase or gene regulation are colored in orange or purple, respectively. MALAT1 is a noncoding RNA and is presented in a rectangle. Targets common to more than one miRNA are indicated with a red border. (B) Classification of targets in functional classes based on PANTHER classification.