Table 1.

List of primary hit compounds.

	Name of compounds	Mechanism of action
1	5′-Amino-5′-deoxyadenosine p-toluenesulfonate salt	Adenosine analog.
2	trans-Azetidine-2,4-dicarboxylic acid	mGluR1 and mGluR5 metabotropic glutamate receptor agonist
3	Chlormethiazole hydrochloride	GABA(A) agonist; glycine receptor modulator
4	beta-Chloro-L-alanine hydrochloride	Alanine aminotransferase inhibitor
5	1,10-Diaminodecane	Inverse agonist at the polyamine recognition site of the NMDA glutamate receptors
6	LY-294,002 hydrochloride	Specific phosphatidylinositol 3-kinase (PI3K) inhibitor.
7	Pentamidine isethionate	NMDA glutamate receptor antagonist
8	PAPP	Selective 5-HT1A serotonin receptor agonist
9	Mebendazole	Glucose transport inhibitor
10	Oxytetracycline	Ribosomal protein synthesis inhibitor
11	Fusidic acid sodium salt	Protein synthesis inhibitor GTPase coupled
12	(S)-(-)-Atenolol	Adrenergic receptor antagonist
13	Tetramisole hydrochloride	Alkaline phosphatase inhibitor