Table 1.
Conserved regions in HCV NS3/4A, NS5A and NS5B.
| Conserved regions (NS3/4A) | Positions |
|---|---|
| APITAY | 1–6 |
| LLSPRP | 126–131 |
| FRAAVC | 154–159 |
| LHAPTGSGKSTKVP | 202–215 |
| VLVLNPSVAATLGFG | 225–239 |
| TYSTYGKFLADGGC | 266–279 |
| IICDECH | 287–293 |
| LGIGTVLDQAETAG | 301–314 |
| VLATATPPGS | 319–328 |
| GEIPFYG | 345–351 |
| KGGRHLIFCHSKKKCDE | 360–376 |
| TDALMTG | 411–417 |
| TGDFDSVIDCN | 419–429 |
| VDFSLDPTF | 436–444 |
| PQDAVSR | 452–458 |
| QRRGRTGRG | 460–468 |
| TPGLPVCQDHL | 519–529 |
| VFTGLT | 535–540 |
| LSQTKQ | 547–552 |
| AYQATVC | 562–568 |
| APPPSWD | 572–579 |
| GPTPLLYRLG | 594–603 |
| TSTWVL | 631–636 |
| Conserved Regions NS5/A | Positions |
| GTFPIN | 86–91 |
| GSQLPC | 185–190 |
| RGSPPS | 220–225 |
| ASSSASQLSAPSL | 227–239 |
| SSMPPLEGEPGDP | 421–433 |
| Conserved Regions NS5B | Positions |
| KKVTFDR | 50–56 |
| TTIMAKNEVF | 136–145 |
| PDLGVRVCEK | 163–172 |
| YGFQYSP | 191–197 |
| YDTRCFDSTVTE | 219–230 |
| CGYRRCRASGV | 274–284 |
| LVCGDDLV | 314–321 |
| FTEAMTRYSAPPGD | 339–352 |
| TSCSSNVSVA | 364–373 |
| YYLTRD | 382–387 |
| ARAAWET | 393–399 |
| PVNSWLGNII | 404–413 |
| MTHFFS | 426–431 |
| YLFNWAV | 524–530 |