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. 2017 Apr 5;7(2):115–120. doi: 10.1007/s13534-017-0025-4

Table 1.

Current techniques for BBB disruption

BBB open techniques Localization Non-invasiveness Stability References
Drug (Mannitol) Bad Good Good [5]
Electroporation Good Bad Bad [6, 7]
Ultrashort-pulsed LASER Good Good Bad [8]
Focused ultrasound Excellent Excellent Excellent [10]