Table 2.
Therapeutic agent delivery after FUS-induced BBB disruption
| Drug | Molar mass/size | Findings | References |
|---|---|---|---|
| Doxorubicin | 579.98 Da | Estimate the amount of doxorubicin delivered | [12] |
| Herceptin | 148 kDa | Estimate the amount of herceptin delivered | [13] |
| Methotrexate | 545.44 Da | Compare to FUS delivery and ICA injection | [14] |
| BCNU | 214 Da | BCNU delivery, long term survival | [15] |
| Epirubicin | 543.5 Da | Epirubicin delivery, tumor progression slowed | [16] |
| Aβ antibody | 150 kDa | BAM-10 delivery, reduction in Aβ plaque | [17] |
| MION-47 | 20 nm | Delivery of nanoparticles (MION-47) | [18] |