Table 3.

Multiple regression showing predictors of health-related quality of life in patients with cancers

	Physical functioning		Role limitations due to physical health		Role limitations due to emotional problems		Vitality		Emotional wellbeing		Social functioning		Pain		General health
	B	P	B	P	B	P	B	P	B	P	B	P	B	P	B	P
(Constant)	54.04		21.81		41.78		55.70		62.70		77.07		66.46		62.86
Female gender	−3.72	.412	3.61	.536	−3.84	.556	0.10	.976	1.09	.720	0.73	.860	−1.92	.623	−2.86	.277
Elderly	−13.79	.001*	1.62	.751	−6.04	.289	−8.11	.005*	1.23	.642	−6.88	.059	0.25	.941	−3.67	.110
University	5.29	.184	0.29	.955	3.89	.496	2.97	.306	1.54	.563	−2.94	.419	4.77	.164	1.10	.632
Employed	3.94	.353	2.88	.598	−2.50	.681	1.50	.627	0.63	.824	−4.56	.240	−3.56	.330	0.13	.956
Married	1.61	.701	−8.98	.096	−4.42	.462	−3.31	.278	−2.42	.388	−5.07	.186	−4.82	.182	−3.41	.160
Obese	−1.57	.667	−4.01	.392	−3.17	.544	2.78	.295	1.45	.550	4.14	.215	−1.27	.685	0.73	.729
Family history of cancer	2.64	.478	−10.3	.033*	−6.55	.221	−4.43	.103	−7.54	.003*	−4.90	.152	−4.14	.197	−1.08	.616
1st year after cancer diagnosis	−1.32	.705	6.74	.133	−3.86	.441	−2.77	.276	−5.20	.027*	−7.34	.022*	−4.28	.155	−6.12	.003*
Breast cancer	8.96	.058	10.38	.088	8.91	.189	−4.24	.218	1.31	.679	−0.19	.965	−1.19	.769	−2.33	.393
Colorectal cancer	−1.77	.712	−0.78	.899	2.00	.771	−5.66	.106	2.16	.502	−2.45	.578	0.10	.981	−4.25	.127
Leukemia cancer	4.09	.556	1.19	.895	−5.06	.613	−7.85	.122	−2.52	.589	−8.16	.201	−0.74	.901	−10.2	.012*
Lymphoma Cancer	−0.78	.905	4.90	.562	10.64	.260	0.82	.863	6.54	.137	6.03	.317	9.13	.107	−0.64	.866
Stage III/IV	−7.82	.042*	−5.15	.297	−10.72	.052	−2.89	.302	−0.17	.947	−9.32	.008*	−2.03	.540	−1.63	.463
Multiple tumors	0.43	.918	−5.98	.272	−5.92	.330	−5.07	.100	−4.14	.144	−5.80	.135	−8.08	.027*	−2.35	.338
Cancer surgery	−0.41	.908	4.37	.340	−0.21	.968	−0.51	.844	0.96	.687	−0.99	.762	0.76	.803	0.72	.727
Chemotherapy	−0.56	.902	−2.23	.705	−2.63	.689	−0.91	.786	1.99	.516	−1.56	.710	−3.77	.340	−1.84	.488
Radiation therapy	−6.08	.078	−5.62	.205	0.01	1.000	−5.92	.019*	−8.05	.001*	−0.82	.794	−4.48	.131	−3.78	.059
Immunotherapy	−5.09	.188	−4.06	.414	−5.42	.329	−5.42	.055	−1.76	.496	−0.39	.912	−7.47	.026	0.71	.751
Antibodies	0.32	.935	6.08	.232	−3.58	.528	2.53	.380	−0.41	.875	0.78	.829	3.12	.360	3.02	.187
Metastasis	−5.68	.219	3.55	.551	−1.99	.764	−4.65	.167	−3.05	.324	−4.21	.321	−6.18	.121	−8.34	.002*
Fever	−0.59	.867	−5.74	.205	−8.41	.097	−2.98	.245	−5.54	.019*	−6.15	.057	−8.01	.009*	−4.93	.016*
Family support	5.38	.353	5.75	.441	4.16	.618	6.75	.111	9.70	.013*	2.12	.689	8.82	.078	7.43	.028*
Chronic disease other than cancer	−0.33	.926	7.47	.102	19.66	.001*	5.11	.048*	0.22	.926	2.58	.427	−2.52	.409	−2.64	.199
Regular exercise	8.82	.013*	7.78	.088	9.75	.056	5.54	.032*	2.45	.301	6.66	.041*	5.76	.060	4.97	.016*
Model summary
F value		3.108	1.496		1.957		2.834		2.448		2.450		3.280		3.269
P value		0.001	0.067		0.006		0.001		0.001		0.001		0.001		0.001
R 2		0.204	0.110		0.139		0.189		0.168		0.168		0.215		0.212
R		0.452	0.331		0.373		0.435		0.410		0.410		0.464		0.461

*Adjusting for other predictors in model, predictor is significant at α = 0.05. B represents the partial regression coefficients. F value represents the test value of overall significance of the linear regression model. R ² represents the proportion of variance explained. R represents multiple correlation coefficients