. 2018 Jun 26;45(13):2342–2357. doi: 10.1007/s00259-018-4075-3

Table 1.

Demographics, neurolinguistic and neuropsychological assessment of the 20 included PPA patients

	Patient number
	2	3	4	12	13	14	16	17	18	19	20	21	1	5	6	8	10	7	9	11
PPA variant	NFV	NFV	NFV	NFV	NFV	NFV	NFV	NFV	NFV	NFV	NFV	NFV	SV	SV	SV	SV	SV	LV	LV	LV
Age (years)	80	57	62	68	76	66	70	65	49	63	70	76	73	71	63	52	55	77	63	74
Gender	M	F	F	F	M	F	M	M	F	M	M	F	F	F	F	F	M	M	F	M
Education (years)	17	16	12	10	12	15	12	15	12	10	10	12	14	8	13	13	14	10	12	18
Handedness	R	R	L	R	R	R	R	R	R	R	R	R	R	R	R	R	R	R	R	R
Symptom duration (months)	33	43	16	60	37	74	39	40	53	29	45	24	19	44	11	131	6	59	95	48
[¹¹C]PIB SUVR	NC	NC	1.26	NC	2.1	1.16	1.35	1.57	NC	1.37	NC	NC	NC	NC	1.12	1.14	1.2	NC	1.81	NC
CSF Aβ₄₂ (pg/ml)	816	1,057	NC	832	477	NC	NC	759	1,077	NC	887	1,144	1,558	733	NC	NC	NC	564	664	321
CSF t-tau (pg/ml)	195	247	NC	320	442	NC	NC	744	231	NC	270	265	428	262	NC	NC	NC	407	NC	858
CSF Aβ₄₂/t-tau	4.18	4.28	NC	2.60	1.08	NC	NC	1.02	4.66	NC	3.29	4.32	3.64	2.80	NC	NC	NC	1.39	NC	0.37
CSF p₁₈₁-tau (pg/ml)	42	34	NC	43	59.6	NC	NC	87.1	31	NC	48	39.9	52	36.3	NC	NC	NC	65.7	NC	95
Amyloid-positivity	−	−	−	−	+	−	−	+	−	−	−	−	−	−	−	−	−	+	+	+
CDR	1	0.5	0.5	0.5	0.5	0	0.5	1	NC	0.5	0.5	0.50	1	0.5	0.5	0.5	0.5	1	0	0.5
MMSE score (/30)	28	24	28	18	24	30	23	5	NC	26	26	18	26	25	29	23	30	26	28	24
CPM score (/36)	26	NC	31	29	29	26	29	24	NC	25	26	17	28	27	34	36	34	32	32	12
BNT score (/60)	52	7	46	30	43	47	41	4	17	53	53	48	11	14	17	9	33	46	57	24
AVF score (1 min)	8	7	12	2	7	13	9	2	NC	16	4	5	7	11	13	6	16	7	23	8
AAT sum single-word comprehension score (/60)	41	56	49	55	41	51	42	37	27	53	51	47	31	32	39	35	58	53	54	50
PALPA auditory word–picture matching score (/40)	40	37	39	39	39	38	39	38	NC	40	40	36	26	27	26	21	39	38	39	38
PALPA verbal associative-semantic high imageability (/15)	11	15	15	10	12	14	14	11	NC	13	10	14	9	15	12	5	14	15	15	15
PALPA verbal associative-semantic low imageability (/15)	12	14	11	7	14	12	11	7	NC	11	9	5	3	7	10	6	14	13	14	12
PPT score (/52)	46	47	47	48	47	48	47	47	NC	49	48	45	31	31	38	34	47	49	52	45
BORB easy B score (/32)	28	31	25	30	29	28	28	29	NC	30	28	27	22	19	22	18	25	28	30	26
BORB hard A score (/32)	25	31	19	22	22	26	24	20	NC	21	30	20	17	19	22	17	26	23	26	21
WEZT verb comprehension score (/60)	56	60	45	40	55	42	52	42	NC	58	55	49	43	32	51	48	58	57	57	53
WEZT auditory sentence comprehension score (/40)	36	29	36	26	33	35	31	12	NC	33	32	23	37	33	38	38	39	27	40	37
WEZT active sentence anagram score (/10)	10	10	10	9	9	10	10	5	NC	10	10	10	10	10	10	10	10	10	10	10
WEZT passive sentence anagram score (/10)	10	10	9	6	9	10	5	5	NC	10	3	5	10	9	10	9	10	10	10	10
AAT cognate word repetition score (/30)	29	28	30	30	16	30	29	NC	5	29	27	30	30	30	28	30	30	30	29	29
AAT sentence repetition score (/30)	27	17	28	24	28	28	28	NC	0	25	23	27	29	29	30	27	30	13	26	24
PALPA single word repetition score (/80)	77	76	80	79	55	80	77	NC	NC	49	76	80	79	77	77	80	79	79	80	80
PALPA pseudoword repetition score (/80)	21	63	72	72	11	78	57	NC	NC	20	59	53	77	69	67	79	77	66	74	56
DIAS diadochokinesis score	103	24	50	51	42	77	115	75	NC	79	18	32	50	70	147	125	80	77	114	117

Values in bold are significantly different from those in healthy controls based on Crawford and Garthwaite [30] or Crawford and Howell [31] statistical procedures

AAT Akense Afasie Test (Aachen Aphasia Test), Aβ_1–42 amyloid-β₄₂, AVF Animal Verbal Fluency, BNT Boston Naming Test, BORB Birmingham Object Recognition Battery, CDR Clinical Dementia Rating scale, [¹¹C]PIB ¹¹C-Pittsburgh Compound B, CPM Coloured Progressive Matrices, CSF cerebrospinal fluid, DIAS Diagnostisch Instrument voor Apraxie van de Spraak (Diagnostic Instrument for Apraxia of Speech), LV logopenic variant, MMSE Mini-Mental State Examination, NFV nonfluent variant, PALPA Psycholinguistic Assessment of Language Processing in Aphasia, PPA primary progressive aphasia, PPT Pyramids and Palm Trees Test, p181-tau phospho181-tau, SUVR standardized uptake value ratio in a composite cortical volume of interest, SV semantic variant, WEZT Werkwoorden En Zinnen Test. NC no data collected