Table 2.

Combinatorial performance of the relative expression of validated miRNAs to distinguish AD from HC

MicroRNA combination	Prediction	AUC	95% CI	CV-AUC
miR-16-5p, miR-125-5p, miR-451a, miR-605-5p	HC versus YOAD	0.976	0.860–0.995	0.9619
miR-16-5p and miR-451a	HC versus YOAD	0.946	0.807–0.987	0.9256
miR-125-5p miR-451a, miR-605-5p	HC versus LOAD	0.847	0.688–0.957	0.751

Prediction binary prediction, AUC area under the curve, CI confidence intervals, CV-AUC k-fold cross-validation AUC