Fig. 5.

miR-153 inhibits the migration of primary HUVECs through suppression of the secretion of ANG1 from MCF7 cells. a MCF7-conditioned media from cells treated with the miR-153 or the ANG1 siRNAs inhibited the migration of the primary HUVECs in a wound healing assay. Representative images are shown. The “CM” means the conditioned medium. b The quantitative results of a. *p < 0.05, **p < 0.01, t test. c The MCF7-conditioned medium with the ectopic ANG1 expression increased the migration of the primary HUVECs and rescued the inhibition of miR-153 by the wound healing assay. The representative images are shown. d The quantitative results of c. *p < 0.05, t test