Fig. 6.

miR-153 inhibits the tube formation of the primary HUVECs through suppressing the secretion of ANG1 from MCF7 cells. a MCF7-conditioned medium with the miR-153 or the ANG1 siRNAs treatment inhibited the tube formation of the primary HUVECs by the tube formation assay. The representative images are shown. The “CM” means the conditioned medium. b The quantitative results of a. *p < 0.05, **p < 0.01, t test. c MCF7-conditioned medium from cells treated with the ectopic ANG1 increased the tube formation of the primary HUVECs and rescued the inhibition of miR-153 as characterized with a tube formation assay. Representative images are shown. d The quantitative results of c. *p < 0.05, **p < 0.01, t test