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. Author manuscript; available in PMC: 2019 Mar 5.
Published in final edited form as: Mol Pharm. 2018 Feb 12;15(3):1180–1191. doi: 10.1021/acs.molpharmaceut.7b01011

Scheme 1.

Scheme 1.

(A) Synthetic scheme of p(OEGMA-co-PDSMA-co-Cy7) nanogel precursors; (B) schematic representation and corresponding reaction scheme of nanogel formulation by first crosslinking of PDS group by reducing agent DTT, then post-modification with poly(ethylene glycol) methyl ether thiol through thiol-disulfide exchange.