Table 1. Disease class, specific diagnosis, age, and sex for cases (CSF samples).

Disease Class	Diagnosis	Age (years)	Gender
Control	Headache	50	F
Control	Transient ischemic attack	77	F
Control	Idiopathic intracranial hypertension	40	F
Control	Headache	55	F
Control	Hydrocephalus/VP shunt	51	F
Control	Headache	33	F
Control	Hydrocephalus/VP Shunt	2	M
Infection	Cryptococcal meningitis/HIV	54	M
Infection	Enterovirus meningitis	19	M
Infection	JC virus/PML/HIV	46	M
Infection	HPeV encephalitis	17	F
Infection	Cryptoccal meningitis post heart transplant	55	M
Infection	WNV encephalitis	33	M
Infection	Lyme disease	48	M
Infection	Toxoplasmosis/status post chemotherapy	73	F
Infection	Cryptococcal meningitis/HIV	42	M
Infection	TB meningitis post adalimumab therapy	30	F
Infection	Staphylococcus epidermidis meningitis/HIV	32	M
Infection	Streptococcus mitis meningitis	73	M
Infection	Viral meningitis, not otherwise specificied	20	F
Infection	TB meningitis/HIV	35	F
Infection	JCV meningitis/immunosuppression for lupus	52	F
Glioma	Anaplastic astrocytoma	77	F
Glioma	Recurrent glioblastoma	60	M
Glioma	Recurrent glioblastoma	50	F
Autoimmune/DM	Autoimmune encephalopathy	53	F
Autoimmune/DM	Post-viral cerebellitis	51	F
Autoimmune/DM	Transverse myelitis	80	F
Autoimmune/DM	CNS vasculitis	27	F
Autoimmune/DM	Paraneoplastic cerebellar dysfunction	55	M
Autoimmune/DM	Acute disseminated encephalomyelitis	39	M
Autoimmune/DM	Acute disseminated encephalomyelitis	80	M
Autoimmune/DM	Anti-acetylcholine ganglionic neuronal receptor autoimmune encephalopathy	66	F
Autoimmune/DM	Multiple sclerosis	29	F
Autoimmune/DM	Multiple sclerosis	30	F
Autoimmune/DM	Multiple sclerosis	46	M
Autoimmune/DM	Tumefactive multiple sclerosis	30	F
Lymphoma	Primary CNS Lymphoma	21	M
Lymphoma	Primary CNS Lymphoma	72	M
Lymphoma	Primary CNS Lymphoma	58	F
Lymphoma	Primary CNS Lymphoma	78	M
Lymphoma	Systemic DLBCL involving CNS	69	F
Lymphoma	Systemic Burkitt lymphoma involving CNS	37	M